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Life Extension, Endothelial Defense with Pomegranate Complete and CORDIART - 60 softgels

  • $69.99
  • $59.99

Blood vessels are lined with a delicate layer of cells known as the endothelium. This endothelial layer is responsible for regulating the health and function of arteries and veins. As you age, protecting the endothelium is critical for maintaining cardiovascular and vascular health. Life Extension’s unique Endothelial Defensewith Pomegranate Complete and CORDIART™ combines three powerful ingredients that have been shown to support a healthy vascular endothelium.

Benefits at a Glance:

  • Supports healthy endothelial function
  • Pomegranate extracts encourage youthful lipid and glucose metabolism and help inhibit inflammatory factors
  • An orally available form of superoxide dismutase (SOD) protects against nitric oxide degradation, which supports healthy arterial function
  • Sweet orange peel extract helps activate endothelial nitric oxide production

Triple-Action Protection for Endothelial Health

This comprehensive formula is made up of the following ingredients shown to support healthy endothelial function:1-7

  • Pomegranate Complete contains polyphenol extracts from every part of the pomegranate, including the seed, flower, and fruit. These extracts have been shown to promote youthful lipid and glucose metabolism1 while inhibiting inflammatory factors2 to support healthy blood flow.3,4
  • GliSODin® is an orally active form of superoxide dismutase (SOD) that has been shown to support healthy arterial function and structure. It boosts levels of the antioxidants SOD and catalase.5-7 Production of SOD declines with age, however, resulting in increased degradation of nitric oxide in the endothelium.  
  • The addition of CORDIART™ (extract from sweet orange peels) to pomegranate provides another vascular benefit by activating endothelial production of nitric oxide, which signals the smooth muscles to relax, inducing vasodilation to support healthy circulation. In clinical research, 500 mg of CORDIART™ alone produced an 18% improvement in flow mediated dilation, a direct marker of endothelial function. CORDIART™ also inhibited the pro-inflammatory factors C-reactive protein and serum amyloid A that interrupt healthy nitric oxide production.8

If you’re ready to give your cardiovascular health a boost, add Endothelial Defense™ with Pomegranate Complete and CORDIART™ to your daily regimen and put the power of pomegranate to work for you.

Suggested Use Read the entire label and follow the directions carefully prior to use. Take two (2) softgels daily before breakfast, or as recommended by a healthcare practitioner.

Supplement Facts
Serving Size: 2 Softgels
Servings Per Container: 30
 Amount Per Serving:% Daily Value
Superoxide Dismutase/Gliadin Complex (GliSODin)
[SOD (Superoxide Dismutase) Enzyme Activity = 500 IU]
500 mg**
Pomella pomegranate extract (fruit)
[std. to 30% punicalagins (120 mg)]
400 mg**
Pomegranate 5:1 extract (fruit)100 mg**
Proprietary pomegranate blend (flower extract and seed oil)
[std. to 22% punicic acid (30 mg)]
137.5 mg**
Cordiart flavonoid glycoside [from immature sweet orange (peel)]
[std. to 90% rutinoside (450 mg)]
500 mg**
**Daily Value not established.

Other Ingredients

Extra virgin olive oil, gelatin, maltodextrin, glycerin, purified water, sunflower lecithin, carob color, beeswax.

Contains wheat.


Caution: Do not take this product if you are allergic to wheat or gluten.

Store tightly closed in a cool, dry place.

  • Keep out of reach of children
  • Do not exceed recommended dose
  • Do not purchase if outer seal is broken or damaged
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating

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